Pathology 1

Match the List I of scientists with their related findings in List II
Choose the appropriate answer given below:

Psammoma bodies are seen in all except:

Dystrophic calcification is seen in

Morphological changes of apoptosis include:
(A) Cytoplasmic blebs
(B) Inflammation
(C) Nuclear fragmentation
(D) Spindle formation
(E) Cell swelling

Caseous necrosis is seen in which of the following:

PAS stains the following except:

Stain useful for identifying premalignant lesions of the lip is:

Neutrophil secretes:
(A) Superoxide dismutase
(B) Myeloperoxidase
(C) Lysosomal enzyme
(D) Catalase
(E) Cathepsin G

Littoral cells are found in

All of the following vascular changes are observed in acute inflammation, except:

Which of the following complement component can be activated is both common as well as alternative pathways?

Which of the following is not an inflammatory mediator?

Cryoprecipitate is rich in which of the following clotting factors?

Prostaglandins are synthesized from:

The role of bradykinin in process of inflammation is:

Given below are two statements.
Statement I: Factor X is a part of both intrinsic and extrinsic pathway.
Statement II: Extrinsic pathway is activated by contact of plasma with negatively charged surfaces.
In the light of the above statements, choose the most appropriate answer from the options given below:

Cause of edema is:

Which of the following is true regarding transudate?
A. It is associated with increased vascular permeability
B. It has a character of Non-inflammatory oedema
C. Protein content is less than 1 gm/dl
D. Oedema in Congestive cardiac failure is the example of transudate
E. Glucose content is less than 60 mg/dl.

Which of the following are Autosomal dominant disease?
A. Adult polycystic kidney
B. Neurofibromatosis-1
C. Neurofibromatosis-2
D. Hereditary spherocytosis
E. Phenylketonuria

All of the following are Autosomal recessive except:

In Marfan‘s syndrome there is defect in protein

A 26-year-old woman presents because of trouble with her vision. Physical examination reveals a very tall, thin woman with long, thin fingers, Examining her eyes reveals the lens of her left eye to be in the anterior chamber. Her blood levels of methionine and cystathionine are within normal levels. Which of the following is the most likely cause of this patient‘s signs and symptoms?

Hemophilia is associated with:

ABO blood group inheritance is an example of:

In Prader Willi syndrome, which of the following is increased?

Maternal disomy of chromosome 15 is seen in:

Two siblings with osteogenesis imperfecta have normal parents. The mode of inheritance is explained by which of the following?

In Huntington chorea the causative mutation in the protein huntingtin is a:

No change of genetic material occurs in which of the following cytogenetic abnormalities?

A married middle aged female gives history of repeated abortions for the past 5 years. The prenatal karyogram of the conceptus is given below:

This karyogram suggests the following:

A 19-year-old female with short stature, wide spread nipples and primary amenorrhea most likely has a karyotype of:

Chromosomal abnormality in Mongolism is:

Barr body is not seen in:

Gene for Wilm‘s tumor is located on:

The technique used for separation and detection of RNA is which one of the following:

All are malignant tumours, except:

Marker of small cell cancer of lung is:

Hamartoma is:

Given below are two statements.
Statement I: Metaplasia is defined as the replacement of one type of cell with another type.
Statement II: Dysplasia often occurs in metaplastic epithelium, but not all metaplastic epithelium is also dysplastic.
In the light of the above statements, choose the most appropriate answer from the options given below: 

Increased risk of cancer is seen in:

Given below are two statements.
Statement I: Quiescent cells, cannot divide in postnatal life
Statement II: Labile cells are present in Liver
In the light of the above statements, choose the most appropriate answer from the options given below: 

Bimodality of incidence occurs in all, except

The tumor suppressor gene p 53 induces cell cycle arrest at:

During which phase of the cell cycle the cellular content of DNA is doubled:

Match the list I of Oncogenes with their associated tumours.
 
Choose the correct answer from the options given below: 

For which one of the following tumors Gastrin is a biochemical marker?

All of the following are examples of tumor markers except:

Osteogenesis imperfecta defect in:

Long and short arm of chromosome are called respectively:

BCL2 is a marker for: